Brian Barkley (born December 8, 1975 in Conroe, Texas) is a former relief pitcher who played for the Boston Red Sox in the 1998 season. Barkley batted and threw left-handed. He is the grandson of Red Barkley, who played for the St. Louis Browns, Boston Bees and Brooklyn Dodgers between 1937 and 1943.
In one-season career, Barkley posted an 0-0 record with two strikeouts in six games pitched.